ECE-GY 6813/BE-GY 6203/BMSC-GA.4426 Medical Imaging
Jointly Offered by Tandon School of Engineering and School of
Medicine, New York University
3 credits, Fall Semester 2018
Course
description:
This course introduces the
physics, instrumentation, and signal processing methods used in X-ray
(projection radiography), X-ray computed tomography, ultrasound imaging,
nuclear medicine (SPECT/PET), and magnetic resonance imaging. The course builds
on fundamental signal processing, basic electricity and magnetism, and
multivariate calculus.
Course
Webpage: http://eeweb.poly.edu/~yao/EL6813
Goals
and Objectives:
·
Familiarity with the basic
biomedical imaging modalities and their history
·
Working knowledge of the
basic physics, engineering and instrumentation principles of each modality
·
Understanding of the typical
applications for each modality
·
Understanding of each
modality strength and weaknesses
·
Current research directions
for each modality
Course
Director:
Prof.
Yao Wang (NYU Tandon School of Engineering)
646-997-3469,
yaowang@nyu.edu
Instructors:
Dr.
Jonathan Mamou (NYU Tandon School of Engineering,
Adjunct Professor) 917-225-0824, jonathan.mamou@nyu.edu, JMamou@RiversideResearch.org
Prof. Steven Baete (NYU School of Medicine),
212-263-4861, steven.baete@nyumc.org
Prof. Daniel Turnbull (NYU School of Medicine)
212-263-7262,
daniel.turnbull@nyumc.org
Prof. Yu-Shin Ding (NYU School of Medicine)
212-263-6605,
yu-shin.ding@nyumc.org
Teaching
Assistant:
Weiwei
Dai (NYU Tandon School of Engineering, Graduate Student) wd471@nyu.edu
Format:
The course is organized as 12
150-minute lectures, two exams, and 1 lecture session used for a tour of
medical imaging facilities. Students will be evaluated based upon course
participation, homework and programming assignments, a midterm exam, a final
exam.
Homework
policy:
Homework will be
assigned weekly and collected a week later. Homework solution will be
provided the following week. Select homework problem will be graded and count
towards the final grade. Exams will be primarily based on homework problems.
There will also be several MATLAB assignments, and these will be collected and
counted towards the final grade.
Grading
policy:
Exam 1: 40%, Exam 2: 40%,
Homework Assignments: 10%, Programming Assignments: 10%.
Lectures:
For lectures 1-6 and both
exams: Friday, 9:50 am-12:20 pm, 2 Metro Tech Center, Rm 9.007, Brooklyn Campus
(NYU Tandon)
For lectures 7-12: Friday,
9:50 am – 12:20 pm, Center for Biomedical Imaging, 3rd floor large
conference room, 660 1st Avenue, New York, NY 10016.
Textbooks:
J. L.
Prince and J. M. Links, Medical imaging: signals and systems, 2/E, Prentice
Hall, 2015. ISBN-10: 0132145189.
Outline:
Lecture
#1 Introduction (September 7, 2018) Lecture note
(updated September 6, 2018)
·
Introduction to the course
·
Overview of medical imaging
modalities (history and basic principles)
·
Review of signals and system
basic concepts
·
Image quality metrics
Lecture #2 Physics of
radiography (September 14, 2018) Lecture
note (updated September 13, 2018)
·
Ionizing radiation
·
Electromagnetic radiation
·
Compton scattering
Lecture #3 Projection
radiography (September 21, 2018) Lecture note (updated
September 18, 2018)
·
X-ray tubes
·
Film/screen detectors
·
conventional x-ray imaging
equation
Lecture #4 X-Ray computed
tomography (CT) part 1 (September 28, 2018) Lecture note (updated September 21,
2018)
·
Instrumentation
·
Image formation
·
Radon transform
Lecture #5 X-Ray computed
tomography (CT) part 2 (September 28, 2018) Lecture note (updated September 28,
2018)
·
Back projection
·
Filtered back projection
·
Image quality
Lecture #6 Nuclear Medicine
(October 5, 2018) Lecture note
(updated October 03, 2018)
·
The physics of nuclear
medicine
·
Positron Emission Tomography
(PET)
MIDTERM EXAM (October 19, 2018) (2011 Fall Midterm) (2011 Fall
Midterm Solution) (2012 Spring Midterm) (2012 Spring Midterm Solution) (2013
Spring Midterm) (2013 Spring Midterm Solution) (2014 Spring Midterm) (2014 Spring
Solution) (2015 Fall Midterm) (2015 Fall Midterm Solution) (2016 Fall Midterm) (2016 Fall Midterm Solution) (2017 Fall Midterm) (2017 Fall
Midterm Solution)
Lecture #7 Physics of
Magnetic Resonance Imaging (October 26, 2018)
·
Magnetization
·
Precession and Larmor frequency
·
RF excitation
·
Relaxation
Lecture #8 Magnetic Resonance
Imaging (November 2, 2018)
·
Instrumentation
·
Data acquisition
·
Image reconstruction
Lecture #9 Advanced Magnetic
Resonance Imaging (November 9, 2018)
·
Image quality
·
Diffusion MRI
·
Functional MRI
Lecture #10 Physics of Ultrasound (November 16, 2018)
·
Acoustic waves: properties of
media
·
Wave propagation: speed,
reflection, attenuation
·
Axial vs Lateral resolution
·
Doppler effect
Lecture #11 Ultrasound Imaging (November 30, 2018)
·
Ultrasound imaging principles
·
Beam pattern formation and
focusing
·
Instrumentation (transducers,
system components)
Lecture #12 Clinical aspects
of PET (December 7, 2018)
· Tracer Development and
Validation
· Drug Pharmacokinetics &
Pharmacodynamics
· Preclinical &
Translational Research
· Clinical Applications
Tour of the NYU Center for
Biomedical Imaging (December 14, 2018)
·
Tour of the RF Lab and explanation
of RF coils components
·
Tour of the MRI facilities
(including a 7T whole body scanner)
·
Practical session at the MRI
console
FINAL EXAM (December 21, 2018)